Home Today's Paper Most Popular Video Gallery Photo Gallery
Subscription Blog Signin Register
Logo
Wednesday, September 20, 2017 11:43:16 AM
Follow Us On: Facebook Twitter Twitter Twitter Twitter

Women at high risk for breast cancer due to certain pathogenic variants

photo by

By
10th-Dec-2016       
Comments
Share your thought
Post a comment »
Read all () »

Life Desk :
The breast cancer causing genes BARD1 and RAD51D are protein in nature. These genes inherit pathogenic variants leading to higher risks of breast cancer in women, finds a research conducted at Mayo Clinic.
"The BARD1 and RAD51D genes, have been included in clinical testing panels to determine breast cancer risk," says Fergus Couch, Ph.D., a geneticist at Mayo Clinic and lead author of the study which was presented at the San Antonio Breast Cancer Symposium
'Not all, but certain pathogenic variant genes like BARD1 and RAD51D are responsible for increasing the risk of breast cancer in women.'
"However, the genes were identified as 'breast cancer' genes through very small studies, so there has never been strong evidence indicating that they are important in driving breast cancer risk."
Dr. Couch and his colleagues studied data from 65,000 women with breast cancer to obtain risk estimates associated with 21 cancer predisposition genes from testing panels.
They found that pathogenic variants in certain genes, such as BARD1 and RAD51D, caused moderately increased risks of breast cancer.
These researchers also confirmed the involvement of the ATM, CHEK2 and PALB2 genes in breast cancer.
They also found that the RAD50 and MRE11A genes did not increase risks of breast cancer.
"Our findings are important, because genes that do not increase risk of breast cancer can now be ignored and potentially removed from clinical testing panels," said Dr. Couch.
Dr. Couch also said, "I am hopeful this work will lead to much better interpretation of results from clinical, hereditary [and] genetic testing."
Source: Eurekalert

Tariff
Add Rate

News Archive

Inside The New Nation

Editorial »

Our inactive diplomacy is deplorable : We shall need armed support


IT'S almost a month since Myanmar has started to push Rohingya Muslims illegally into Bangladesh; creating a burden for an economically weaker country like ours. Our government waiting eagerly for the international power houses to act quickly and solve the problem for us. But all our so-called proven friends like ...

Entertainment »

Antora Azim`s web series Basic Ali


Sheikh Arif Bulbon :Few years ago, Antora Azim started her acting career through Adnan Al Rajib’s a play titled Middle Class Sentiment. Under his direction Antora also performed as a model in a TV commercial of Banglalink. Later she took break from media for her study. She again started shooting ...

Entertainment »

Bhoomi item song by Sunny Leone faces Censor scissors - fans to face disappointment


The Censor Board always has a last laugh because of the immense powers vested with it. And with power comes responsibility. The Central Board of Film Certification is a statutory censorship and classification body under the Ministry of Information and Broadcasting, Government of India. Bhoomi has been at the receiving ...

City »

BNP Standing Committee Member Amir Khasru Mahmud Chowdhury, among others, at a discussion on `Bangladesh`s Position in Rohingya Crises` organised by Bangladesh Youth Forum at the Jatiya Press Club on Tuesday.


International »

Trump expresses his hopes for peaceful settlement to ME crisis


AFP, United Nations :US President Donald Trump again expressed his hopes for a peaceful settlement to the Middle East crisis Monday as he met Israel's Prime Minister Benjamin Netanyahu.Netanyahu was the first leader to have a one-on-one with Trump at the US president's first United Nations General Assembly, an annual ...

International »

Hong Kong leader demands end of independence talk


Reuters, Hong Kong  :Hong Kong's leader urged an immediate end to independence debates in the Chinese-ruled global financial hub on Tuesday, warning that the issue was harming the city's relationship with Beijing's Communist Party leaders.Insisting that the government did not want to intervene on university campuses, Chief Executive Carrie Lam ...

Sports »

Canada`s Brayden Schnur (right) and India`s Yuki Bhambri shake hands after the match during Davis Cup singles tennis tournament action in Edmonton, Alberta on Sunday.


Editorial »

Rice crisis must be resolved — police action not enough


THE government on day before yesterday directed the law enforcement agencies and Deputy Commissioners (DC) to arrest illegal rice hoarders in the country. The directive comes in the wake of introducing open market sales (OMS) of coarse rice at Tk. 30 per kg, double the previous year's price, across the ...

City »

Hefazat-e-Islam Bangladesh brought out a procession in the city protesting persecution of Rohingya Muslims in Myanmar was intercepted by police at Shantinagar intersection on Monday.


Entertainment »

Waluscha De Sousa sets the ramp on fire in an Anj Kreations lehenga


A fashion favourite & Bollywood actress Waluscha De Sousa who made her debut in Shah Rukh Khan starrer Fan was seen walking the ramp at a preview show for an upcoming exhibition named Joya. This exhibition organised by the Moranis of Cineyug held a preview of top 8 designers participating ...

International »

US may stay in Paris climate accord : Tillerson


Reuters, Washington :The United States could remain in the Paris climate accord under the right conditions, Secretary of State Rex Tillerson said on Sunday, signaling a shift in tone from the Trump administration, which angered allies with its decision to pull out of the agreement.President Donald Trump is willing to ...

Editorial »

N. Korea`s mad rush for nuclear status


NORTH Korea said it was seeking military "equilibrium" with the United States as leader Kim Jong-Un vowed to complete Pyongyang's nuclear programme. North Korea successfully fired a Hwasong-12 intermediate-range ballistic missile over Japan on Friday, responding to a new round of UN sanctions over its sixth nuclear test with its ...

Sports »

Saida Akter Mou (right) of Bangladesh Ansar & VDP and Rifad Ahmed Sabbir of BKSP pose with their trophies of the girls' singles and boys' singles of the South Bangla Agriculture & Commerce Bank 4th National Junior Table Tennis Championship at the Shaheed Tajuddin Wooden Floor Gymnasium on Sunday.


Entertainment »

Kriti Sanon marks Nat`l Engineers Day


It is a known fact that Kriti Sanon who is today known to be one of the top young actresses in the industry has a background of being an Engineer. The Bareilly Ki Barfi actress came to Mumbai a few years back from Delhi where she was studying engineering with a ...

City »

Jatiyatabadi Projanma `71, organized a discussion titled `Election-time Government: Role of Election Commission and future of democracy at the Jatiya Press Club on Sunday. Among others, BNP Senior Joint Secretary General Ruhul Kabir Rizvi took part in the discussion.


 
Items that you save may be read at any time on your computer, iPad, iPhone or Android devices.
 
Are you new to our website? Do you have already an account at our website?
Create An Account Log in here
Email this news to a friend or like someone
Email:
Write a comment to this news