Home Today's Paper Most Popular Video Gallery Photo Gallery
Subscription Blog Signin Register
Logo
Saturday, December 16, 2017 05:36:58 AM
Follow Us On: Facebook Twitter Twitter Twitter Twitter
BREAKING NEWS:

Pathological intervention during brain tumor operation

photo by

By
17th-Feb-2017       
Comments
Share your thought
Post a comment »
Read all () »

Life Desk :
Today's workflow for determining a diagnosis during an operation requires the surgeon wait for 30 to 40 minutes while tissue is sent to a dedicated pathology lab for processing, sectioning, staining, mounting and interpretation. The entire team in the operating room may be idle while waiting for pathology results. A more efficient surgical procedure would save money by requiring less time in the operating room.
'Stimulated Raman histology improved speed and diagnostic efficiency, in an operating room. This could change the pace and structure of an operation.' Neurosurgeons and pathologists at Michigan Medicine are the first to execute stimulated Raman histology, a method that improves speed and diagnostic efficiency, in an operating room. They detail the advance in a new Nature Biomedical Engineering paper. The researchers imaged tissue from 101 neurosurgical patients using conventional methods and the new method. Both techniques, they found, produced accurate results but the new method was much faster. That, if applied widely, could change the pace and structure of an operation.
"By achieving excellent image quality in fresh tissues, we're able to make a diagnosis during surgery," says first author Daniel A. Orringer, assistant professor of neurosurgery at the University of Michigan Medical School. "This eliminates the lengthy process of sending tissues out of the OR for processing and interpretation."
"Our technique may disrupt the intraoperative diagnosis process in a great way, reducing it from a 30-minute process to about three minutes," Orringer says. "Initially, we developed this technology as a means of helping surgeons detect microscopic tumor, but we found the technology was capable of much more than guiding surgery."
Near-perfect agreement
Stimulated Raman scattering microscopy, the technology behind SRH, was developed in 2008, but the hazardous lasers it involved made it unsuitable for use in an operating room. A clinical version has now been developed and tested in the operating room for more than a year at U-M, with the fiber-laser-based microscope mounted right onto a clinical cart that plugs into the wall. To interpret the samples, researchers developed SRH, which creates images familiar to those currently in use.SRH uses virtual coloring to highlight the cellular and architectural features of brain tumors, with a result resembling traditional staining. The pathologist is then able to differentiate the tumor tissue from normal brain as usual. "It's very similar to what we currently do in our intraoperative diagnosis, with the exception that the tissue is fresh, has not been processed or stained," says senior author Sandra Camelo-Piragua, assistant professor of pathology at the U-M Medical School. In the Nature Biomedical Engineering study, neuropathologists were given 30 specimen samples, processed via SRH or traditional methods. They were told the same information about each patient's medical history and the location of the tumor and asked to make a diagnosis. Those pathologists, the U-M researchers found, were equally likely to make a correct diagnosis whether they used SRH or conventional slides."SRH imaging will ensure that appropriate and good quality tissue is collected to reach our ultimate goal: accurate diagnosis," Camelo-Piragua says.
Artificial intelligence
As Orringer and his team continue to improve this imaging technology, they're also teaching a computer how to use SRH images to make diagnoses. They built and validated a machine learning process that was able to predict brain tumor subtype with 90 percent accuracy in a subset of 30 patient samples. "The more we feed the computer, the more accurate its diagnoses will become," Orringer says.
Connecting hospitals
Using SRH might also improve the workflow for facilities without access to expert neuropathologists. Orringer notes that smaller hospitals may be able to partner with larger systems that do have access, since there are fewer than 800 board-certified neuropathologists compared to the approximately 1,400 U.S. institutions performing brain surgery.
"Bringing the SRH to smaller hospitals would extend their capabilities because the images can be interpreted remotely," he says. Sample preparation is minimal and the SRH could quickly deliver virtual histologic sections to aid diagnosis remotely. The next step is a large-scale clinical trial, with an eventual goal of showing equivalence between SRH technique for making diagnoses, Orringer says. The prototype system is currently intended for research use only.
-  Source: Eurekalert

Tariff
Add Rate

News Archive

Inside The New Nation

International »

Trump promises `giant tax cut` as `Christmas gift` to Americans


PTI, Washington :US President Donald Trump today said the Congress has reached an agreement on tax legislation that will deliver more jobs, higher wages, and "massive tax relief" for American families and domestic companies.Trump recognised the tax reform as a campaign promise during his run-up to the 2016 presidential election, ...

Editorial »

Muslim leaders must continue to act together not to be ignored


WE welcome the OIC's (Organisation of Islamic Cooperation) decision declaring East Jerusalem as capital of Palestine at a summit at Istanbul on Wednesday as the most appropriate and timely action to denounce US President Donald Trump's unilateral declaration that Jerusalem is the capital of the state of Israel. Their call ...

Football »

Players of A Level team, the champions of the Inter-Class Victory Day Football Competition of Manarat Dhaka International School & College with the teachers of Manarat Dhaka International School & College pose for a photo session at Manarat College field on Thursday.


Entertainment »

Meryl Streep is the most Golden Globe-nominated actor


Meryl Streep has begun her Hollywood award season dominance by bagging her 31st Golden Globe nomination, which is a record in the 75-year history of the award show. Streep won the nomination in the best actress, drama category for her portrayal of the Washington Post publisher Kay Graham in Steven ...

Entertainment »

Porimoni, Zayed Khan`s Antorjwala releases today


Entertainment Report :Today across the country in 175 cinema halls Malek Afsari directed and Porimoni-Zayed Khan acted much awaited movie Antorjwala is set to be released. On the occasion its releasing Pori and Zayed will enjoy the movie along with director Malek Afsari in Dhaka’s Modhumita, Shyamoli and Sony halls.While ...

City »

Speaker Dr Shirin Sharmin Chowdhury handing over ICT Award to Director General of Health Department Prof Dr Abul Kalam Azad for his contribution in using digital technology in health services at Bangabandhu International Conference Center in the city on Tuesday.


Weekend Plus »

Quick recipes for the burger-lover in you


Weekend Plus Desk :If you are a burger lover or want to fix a burger quickly for uninvited guests, here are a few recipes which can save the day. Recipes by Chef Gaurav Chadha, in-house chef, Dr Oetker India Pvt Ltd:* Chicken and egg burger: Heat oil in a kadhai ...

Editorial »

Attack on New York City is disgusting


AN attempted terrorist attack in a New York City bus terminal by a US national of Bangladesh origin has caused widespread surprise and condemnation here and also in the Bangladesh community in the USA. The person Akayed Ullah at his 27 is a taxi driver in New York City and ...

International »

US embassy unlikely to move to Jerusalem before 2020: Tillerson


Xinhua, Washington :U.S. Secretary of State Rex Tillerson said Tuesday the U.S. embassy in Israel was unlikely to be moved to Jerusalem before 2020, national media outlets reported."It's not going to be anything that happens right away," U.S. news daily the New York Times quoted Tillerson's speech at the State ...

Football »

Crystal Palace's James McArthur (centre) celebrates scoring his side's second goal of the game with team-mates during the English Premier League match between Crystal Palace versus Watford at Selhurst Park, London on Tuesday.


Sports »

A scene from the SA Group Premier Division Chess League at the Auditorium of the National Sports Council Tower on Wednesday.


Entertainment »

Akshay shares the new poster of PadMan while giving the hint about trailer


Akshay Kumar is gearing up for his next release PadMan which is all set to release on Republic Day, 26th January 2018. Recently Akshay is on spree of releasing new posters of the films. A day before yesterday Akshay shared a poster of the film in which he can be ...

City »

DU VC Prof Aktaruzzaman speaking at a seminar on' Mass Media Vs Social Media at TSC organised by the Dhaka University Journalists Association on Wednesday .


Editorial »

Colleges without enrolment should cease to exist


OVER 1,500 colleges are in fear of closure as they have failed to fulfil the condition of the Education Ministry in terms of students' admission at Higher Secondary level, The concern is genuine because opening of new colleges and also their closure is not small thing, as it impacts lives ...

Cricket »

A good number of spectators arrived at the Sher-e-Bangla National Cricket Stadium to watch the final match of the AKS Bangladesh Premier League (BPL) Twenty20 Cricket between Rangpur Riders and Dhaka Dynamites at the Sher-e-Bangla National Cricket Stadium in the city's Mirpur on Tuesday.


 
Items that you save may be read at any time on your computer, iPad, iPhone or Android devices.
 
Are you new to our website? Do you have already an account at our website?
Create An Account Log in here
Email this news to a friend or like someone
Email:
Write a comment to this news