Home Today's Paper Most Popular Video Gallery Photo Gallery
Subscription Blog Signin Register
Logo
Thursday, January 18, 2018 07:54:45 AM
Follow Us On: Facebook Twitter Twitter Twitter Twitter

Sea cucumber genome can help in the study of tissue regeneration

photo by

By
04th-Nov-2017       
Comments
Share your thought
Post a comment »
Read all () »

Life Desk  :
Sea cucumbers form one class of the echinoderms that also includes sea urchins and star fish. They have a unique genome structure that has the ability to regenerate damaged or lost body parts. Owing to this property, the sea cucumber is a particularly promising model animal for regenerative medicine.
Sea cucumber has a radically different skeletal structure and a genome structure that explains the reason behind its ability to regenerate.
The research findings that identified the high-definition genome sequence of the sea cucumber may be useful for understanding evolution of the animal kingdom.
'Sea cucumbers are unique among echinoderms in not having a hardened calcium exoskeleton, and in their capacity to regenerate damaged or lost body parts.'
Sea Cucumbers - What are They?
Sea cucumbers form one class of the echinoderms, a phylum that also includes sea urchins and sea stars ("star fish"). Echinoderms and chordates (a closely related phylum that includes humans) share a feature that distinguishes them from most other animals: they are so-called deuterostomes, in which the anus, rather than the mouth, forms first in development.
Sea cucumbers are unique among echinoderms in not having a hardened calcium exoskeleton, and in their capacity to regenerate damaged or lost body parts and viscera to a much greater extent than sea urchins or sea stars.
To explore the genetic underpinnings of these features, and to better understand the evolution of the deuterostomes, the authors performed high-definition genomic sequencing of the sea cucumber Apostichopus japonicus (also known as the Japanese sea cucumber), covering about 92% of its estimated 880 megabases of DNA, including more than 30,000 genes.
By comparing the genome of A. japonicus with that of other organisms, the authors found evidence that the echinoderms diverged from hemichordates (a small group of marine deuterostomes that includes the acorn worms) about 533 million years ago and the sea cucumbers split off from other the echinoderm classes about 479 million years ago.
The authors showed that while the sea urchin genome includes 31 genes for biomineralization, critical for forming a calcified skeleton, the sea cucumber has only seven such genes. They also found that the sea cucumber expressed these biomineralization genes at much lower levels throughout development, likely accounting for their softer bodies compared to sea urchins.As a strategy to scare off predators, sea cucumbers can expel their viscera, which they can then regenerate within several weeks. The authors found a group of duplicated genes, called PSP94-like genes, that were specifically expressed in the regenerating intestines of the sea cucumber. These genes which had no corresponding genes in other echinoderms, suggesting that these genes may be crucial to the animals' ability to quickly regrow their viscera.
A second group of genes, called fibrinogen-related proteins, were also duplicated and highly expressed during regeneration, indicating they likely contribute to this ability as well.
"The sea cucumber is a particularly promising model animal for regenerative medicine," said Xiang, and the availability of its genome should aid efforts to study the biology of regeneration and determine if echinoderm regrowth can offer insights that can be applied to human medicine.
"Our findings should also facilitate the understanding of the requirements for sustainable utilization and effective breeding of echinoderms, in support of the high-value sea cucumber industry," which includes its use as a source of food and traditional Chinese medicine.
Source: Medindia

Tariff
Add Rate

News Archive

Inside The New Nation

Business & Economy »

Filippo Lanzi, new head of Asia Pacific GSK Consumer Healthcare


Business Desk :GlaxoSmithKline (GSK) Consumer Healthcare has announced the appointment of Filippo Lanzi as its regional head of the Asia Pacific, encompassing 23 territories. Lanzi is also the newest member of the Consumer Healthcare Strategic Leadership Team and the GSK Singapore Country Board.Lanzi joined GSK as part of a joint ...

International »

US govt shutdown looms amid harsh immigration exchange


Reuters, Washington :Partisan finger-pointing over immigration policy on Tuesday left the U.S. Congress and the White House stumbling closer to a possible federal government shutdown by the end of the week, although Wall Street held out hopes for a deal to prevent that.Republicans who control Congress are expected to try ...

Editorial »

Be careful about corruption over the big projects


Finance Minister AMA Muhith has said the China Harbour Engineering Company Limited that got the contract for expansion of Dhaka-Sylhet Highway had bribed government officials. So, the government "blacklisted" the firm and decided to fund the expansion work of the 226km Dhaka-Sylhet road to a four-lane highway on its own, ...

Sports »

Anett Kontaveit of Estonia makes a forehand return to Germany's Mona Barthel during their second round match at the Australian Open tennis championships in Melbourne, Australia on Wednesday.


Entertainment »

Valentine’s Day telefilm Mithojeebi


Sheikh Arif Bulbon :On the occasion of coming Valentine’s Day, Mir Sabbir and Moutushi Biswas acted together under Azizul Hakim’s direction in a special telefilm titled Mithojeebi scripted by Zinat Hakim to telecast on Channel i. Both Sabbir and Moutushi acted under Azizul Hakim for the first time. Zinat Hakim ...

City »

BNP Chairperson Begum Khaleda Zia appeared before the special court on Bakshi Bazar Alia Madrasha premises in the city yesterday on two corruption cases filed by Anti-Corruption Commission.


Editorial »

Lies about economic progress are coming out


The economy has come under pressure due to the banking sector crisis, inflation and soaring imports amid inadequate export earnings and insufficient remittance inflows, the Centre for Policy Dialogue (CPD) said recently. The banking sector is suffering from cronyism, the think-tank said, adding that various irregularities and embezzlement of public ...

Sports »

Petra Kvitova of the Czech Republic makes a forehand return to Germany's Andrea Petkovic during their first round match at the Australian Open tennis championships in Melbourne, Australia on Tuesday.


Entertainment »

Much-awaited intense and gripping trailer of Breathe


After tantalizing the senses of audiences with the edge of the seat teaser, Amazon Prime Video and Abundantia Entertainment have now released the much-awaited trailer of Breathe. Breathe brings to the audience R Madhavan in the OTT space for the very first time. The trailer of the digital series is ...

Entertainment »

Richi works in a serial after returning country


Sheikh Arif Bulbon :Popular TV actress Richi Solaiman returned to Bangladesh on December 8. This time she came here to pass time only with her family and close persons of media. Despite having earlier schedule to come to country Richi did not agree to work for this reason. After returning ...

International »

We will `strangle` US-backed force in Syria `before it`s even born`: Erdogan


Reuters: Beirut :Turkey's Tayyip Erdogan threatened on Monday to "strangle" a planned 30,000-strong US-backed force in Syria "before it's even born," as Washington's backing for Kurdish fighters drove a wedge into relations with one of its main Middle East allies.The United States announced its support on Sunday for plans for ...

International »

Melania, America's enigmatic first lady


AFP, New York :Groomed to perfection yet rarely heard in public, Melania Trump is an enigma-a first lady whose opinions, marriage and goals remain a mystery to millions of Americans.She is without question a unique first lady: a former model who once posed nude in her husband's private jet; the ...

Business & Economy »

NRBC Bank aims to woo investment, quality banking


Kazi Zahidul Hasan  :NRB Commercial (NRBC) Bank Ltd has taken steps to bring substantial amount of foreign investment mainly from expatriate Bangladeshis this year in line with the objective it stated in the founding charter. "The bank was established to bring investment of non-resident Bangladeshi (NRBs) but it slipped from ...

Business & Economy »

Syed Waseque Md. Ali, Managing Director of First Security Islami Bank Limited, poses with the participants of the 28th Foundation Course at its Training Institute in the city recently. Senior officials of the bank were present.


City »

BNP Chairperson Begum Khaleda Zia appeared before the special court on Bakshi Bazar Alia Madrasha premises in the city on Tuesday on two corruption cases filed by Anti-Corruption Commission.


 
Items that you save may be read at any time on your computer, iPad, iPhone or Android devices.
 
Are you new to our website? Do you have already an account at our website?
Create An Account Log in here
Email this news to a friend or like someone
Email:
Write a comment to this news