Home Today's Paper Most Popular Video Gallery Photo Gallery
Subscription Blog Signin Register
Logo
Friday, August 23, 2019 09:28:24 AM
Follow Us On: Facebook Twitter Twitter Twitter Twitter

Mushrooms can aid in diabetes treatment

photo by

By
25th-Aug-2018       
Comments
Share your thought
Post a comment »
Read all () »

Life Desk :
White button mushrooms act as a prebiotic and can help improve microbial community in the gut, which aid in glucose regulation in the liver.
The research team also suggest that better understanding this connection between mushrooms and gut microbes in mice could one day pave the way for new diabetes treatments and prevention strategies for people.
'Daily consumption of white button mushrooms can aid in the regulation of glucose in the liver, thereby helps in the management of diabetes.'
In the study, the researchers showed that feeding white button mushrooms to mice changed the composition of gut microbes - microbiota - to produce more short chain fatty acids, specifically propionate from succinate, according to Margherita T. Cantorna, Distinguished Professor of Molecular Immunology in Penn State's College of Agricultural Sciences. Previous research has shown that succinate and propionate can change the expression of genes needed to manage glucose production, she said.
"Managing glucose better has implications for diabetes, as well as other metabolic diseases," said Cantorna.
Normally glucose is provided from the food people eat. Insulin moves glucose out of the blood and into the cells. Diabetes occurs when either there is not enough insulin or the insulin that is made is not effective, resulting in high blood glucose levels.
Diabetes and pre-diabetes contribute to severe life threatening diseases including heart disease and stroke. According to the Centers for Disease Control, 100 million Americans have diabetes or pre-diabetes in 2017.
The researchers, who reported their findings in a recent issue of the Journal of Functional Foods, available online now, used two types of mice in the study. One group of mice had microbiota, the other group did not have microbiota and were germ-free mice.
"You can compare the mice with the microbiota with the germ-free mice to get an idea of the contributions of the microbiota," said Cantorna. "There were big differences in the kinds of metabolites we found in the gastrointestinal tract, as well as in the liver and serum, of the animals fed mushrooms that had microbiota than the ones that didn't."
The researchers fed the mice about a daily serving size of the mushrooms. For humans, a daily serving size would be about 3 ounces.
According to the researchers, consuming the mushrooms can set off a chain reaction among the gut bacteria, expanding the population of Prevotella, a bacteria that produces propionate and succinate, said Cantorna. These acids can change the expression of genes that are key to the pathway between the brain and the gut that helps manage the production of glucose, or gluconeogenesis.
According to the researchers, the mushrooms, in this case, serve as a prebiotic, which is a substance that feeds beneficial bacteria that are already existing in the gut. Probiotics are live beneficial bacteria that are introduced into the digestive system.
Beyond the possible beneficial benefits of mushrooms as a prebiotic, Cantorna said that this study also shows more evidence that there is a tight connection between diet and microbiota.
"It's pretty clear that almost any change you make to the diet, changes the microbiota," said Cantorna.
Cantorna said that the study was done with lean mice, but they are interested in what the reaction would be in obese mice. Eventually, the team would like to see how this works in obese mice and, eventually, in humans, she added.
Source: Eurekalert

Tariff
Add Rate

News Archive

Inside The New Nation

Entertainment »

Radhika Apte has given us character to remember forever


Indie Star Radhika Apte became the talk of the town for her earthy and unconventional character. It was the actress’ character from Manjhi: The Mountain Man which made us all believe in how chaos in beautiful and garnered appreciation from all across. Celebrating the highly critically acclaimed film, Radhika is ...

Editorial »

ACC fails to gain trust of common people


THE 11 ACC officials whose faulty and biased investigation led to wrongful imprisonment of Jaha Alam for three years have been promoted to senior ranks. Even the Anti-Corruption Commission's (ACC) own investigation acknowledged that Jaha Alam had to lose three years of his life in prison because these officials "erroneously ...

Cricket »

Afghanistan Test a preparation platform for Indian series: Mominul


Bangladesh will take the one-off Test match against Afghanistan as part of their preparation for the two-match Test series against India, with which they will begin the journey of ICC World Test Championship.As India is blessed with some world class spinners who could demolish any side at their home den, ...

International »

Putin says US missile test raises new threats to Russia


AP, Helsinki :Russian President Vladimir Putin said Wednesday that the test of a new U.S. missile banned under a now-defunct arms treaty has raised new threats to Russia and will warrant a response.The U.S. tested a modified ground-launched version of a Navy Tomahawk cruise missile that accurately struck its target ...

Editorial »

Muhith can't be blamed, he is part of the system


National Board of Revenue has allowed former finance minister AMA Muhith to release an imported car under the duty-free scheme meant for the Members of Parliament. The NBR on Monday issued a special order exempting Muhith from payment of all types of import duty, value-added tax and supplementary duty to ...

Editorial »

We have to see positive results in our relations with India


INDIAN External Affairs Minister S Jaishankar on Monday reconfirmed his government's stance on most-hyped Teesta water-sharing treaty that remained "unchanged" and "mutually acceptable formula" for sharing water of 54 common rivers. The three-day visit of the top Indian envoy has taken place at a time when the Indian government is ...

Football »

Ribery set for two-year deal at Fiorentina pending medical


Franck Ribery has landed in Florence and will undergo a medical ahead of completing a free transfer to Fiorentina.The 36-year-old left Bayern Munich in June after 12 years at the club and will now sign a two-year deal with the Serie A side worth almost £4.1m (€4.5m) per season, according ...

Entertainment »

Swastika shuts down malicious troll like a boss


As we say, ‘no one is perfect,’ the myth of ‘perfect body’ is quite a tough role to live up to and our silver screen celebrities have always been under a constant surveillance of the hypocritical body shamers. For even an ounce of extra weight gain or a shred from ...

International »

Johnson, Merkel to face off in first Brexit talks


AFP, Berlin :British Prime Minister Boris Johnson visits Berlin on Wednesday to kick off a marathon of tense talks with key European and international leaders as the threat of a chaotic no-deal Brexit looms.On his first foreign visit since taking office, he will seek to convince German Chancellor Angela Merkel, ...

International »

US ready to resume nuclear talks with North Korea


AFP, Seoul : The United States is ready to sit down with North Korea to resume long-awaited working-level nuclear talks, a US envoy said on Wednesday.Nuclear discussions between Washington and Pyongyang have stalled since a second summit in Hanoi in February ended without an agreement over differences on the extent of ...

Editorial »

DCCs' dengue drama


AS Bangladesh, especially the capital is reeling under massive dengue outbreak, mobile courts run by Dhaka's two city corporations are penalising the residents keeping public places and government establishments hosting aedes mosquito breeding grounds out of purview.Dengue has already claimed at least 113 lives and at least 55,000 dengue patients ...

Cricket »

'Frightening' Archer won't let-up against Australia, says Stokes


England's Ben Stokes has told Australia to expect more bouncers from Jofra Archer in the remainder of the Ashes."It's part of the game and a big part of Jofra's game, being aggressive, not letting batsmen settle," said Stokes.World Cup-winning fast bowler Archer produced a hostile and compelling display on debut ...

International »

US tests first ground-launched cruise missile after INF Treaty exit


Reuters, Washington :The Pentagon said on Monday it tested a conventionally configured ground-launched cruise missile with a range of more than 500 km (310 miles), the first such test since the United States pulled out of the Intermediate-range Nuclear Forces Treaty (INF).The United States formally withdrew from the landmark 1987 ...

International »

Johnson tells EU he wants Brexit deal but without backstop


British Prime Minister Boris Johnson wrote Monday to EU President Donald Tusk reaffirming his desire to conclude a Brexit deal as well as his opposition to the controversial "backstop" on Ireland.The so-called backstop is a mechanism that would keep the UK in EU customs arrangements to prevent a hard border ...

Business & Economy »

Md. Arfan Ali, Managing Director of Bank Asia Limited, inaugurating its Reporting Hub to ensure automated reporting of foreign trade related transactions for secured customer service at Tejgaon Link Road branch of the bank in the city on Tuesday. Mohammad Borhanuddin, Md. Sazzad Hossain, DMDs and Md. Zia Arfin, Head of International Division of the bank were also present.


 
Items that you save may be read at any time on your computer, iPad, iPhone or Android devices.
 
Are you new to our website? Do you have already an account at our website?
Create An Account Log in here
Email this news to a friend or like someone
Email:
Write a comment to this news